Inhibition by derivatives of rifamycin of soluble ribonucleic acid polymerase from rat liver.
نویسندگان
چکیده
merase (EC 2.7.7.6) have been demonstrated in eukaryotic cells (Roeder & Rutter, 1969; Jacob et al., 1970a; Kedinger et al., 1970; Mondal et al., 1970; Horgen & Griffin, 1971; Strain et al., 1971). RNA polymerase I (or A), which is associated with the nucleolus (Roeder & Rutter, 1970), is probably engaged in the transcription of nucleolar genes to form rRNA (Blatti et al., 1970; Tocchini-Valentini & Crippa, 1970; Zylber & Penman, 1971), whereas RNA polymerase II (or B), which is present in the nucleoplasmic fraction (Roeder & Rutter, 1970a), is probably making extranucleolar nuclear RNA, including heterogeneous nRNA and mRNA (Blatti
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ورودعنوان ژورنال:
- The Biochemical journal
دوره 128 5 شماره
صفحات -
تاریخ انتشار 1972